Careers at ThermoFisher Scientific

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Job ID :
Location :
US - California - Fremont
Job Description

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

How will you make an impact?

The Clinical Diagnostics Division of Thermo Fisher Scientific is seeking a highly motivated, innovative and experienced Organic - Medicinal Chemist to join the R&D department. The Fremont site is a Center of Excellence for in vitro diagnostic medical device development, manufacturing and commercialization in the heart of Silicon Valley. Our state-of-the-art laboratories are equipped with a broad array of HPLCs, mass specs and other analytical instrumentation.

The Organic - Medical Chemist is a hands-on bench scientist position responsible for developing Rare Reagents to support R&D and production with activities in product development, product transfer, product improvement and production. The ideal candidate shall have wide range of specialized experimental techniques and skills in their application, exercise independent judgment in developing methods and techniques, strong capabilities of resolving issues in creative ways and advocating corrective action, excellent communication and interpersonal skills that cultivate collaborations for maximum efficiency.

What will you do?

  • Design and synthesize protein conjugates and novel reagents for in vitro diagnostic medical device products, including drug derivatives, linker arms enzyme conjugates, and immunogens
  • Synthesize and purify compounds involving multistep synthesis from milligram- to multi-gram scale
  • Plan and execute multiple reactions simultaneously
  • Interpret and properly document results of various experiments and present the data at group meetings
  • Conduct, direct and troubleshoot potentially highly complex technical experiments to achieve department and company goals
  • Perform other responsibilities to support the needs of the department as assigned
  • Follow Good Laboratory Practices (GLP) and good documentation practices including lab notebook, MPIs, SOPs and other necessary documentation
  • Comply with Design Controls, Good Manufacturing Practices (GMP) and International Organization for Standardization (ISO) guidelines, which includes, for example, process validation
  • Work independently with little supervision
  • Thorough documentation of experimental procedures - writing of reports and technical documents
  • Achieve a high level of productivity in the laboratory setting, as well as being able to demonstrate the ability to resolve key project hurdles and assumptions by effectively using available information and technical expertise
  • Maintain a safe, pleasant and efficient working environment.

How will you get here?

  • Bachelor's degree plus 5-7 years of experience or Master's with 3+ years of experience or a Ph.D with 1-2 years of experience in Organic Chemistry.
  • Requires in depth knowledge of Organic Chemistry synthesis and purification of organic reagents, chromatographic and spectroscopic analysis, documentation of results and procedures
  • Must be able to work under pressure and coordinate numerous activities with a multi-disciplinary team of scientists who need to communicate and cooperate to achieve maximum efficiency
  • Excellent written and oral communication skills
  • Excellent organization and strong project management skills
  • Experience as a synthetic Organic or Medicinal Chemist in an industrial laboratory is preferred
  • Possess a strong background in the theory and practice of synthetic organic chemistry, possess excellent problem solving skills and demonstrate a thorough understanding of synthetic methods and reaction mechanisms
  • Experience in drug conjugates synthesis and techniques
  • Must be able to independently prioritize own work assignments, and consistently demonstrate the ability to perform assigned tasks through rigorous data collection and applying analytical tests and instrumentation in the laboratory
  • Must have expertise in the purification and characterization of organic compounds using applicable modern techniques
  • Self-motivated, independent, team player and a proactive driving force of efficient execution
  • Capable of multi-tasking and changing priorities caused by time, markets, customers, budget or other constraints
  • Proficient with Excel, PowerPoint, ChemDraw and Scifinder
  • Experienced in the use of HPLC, LCMS, Automated purification systems, and UV-VIS
  • Proficient in the interpretation of NMR data
  • Experience working in a GMP environment

At Thermo Fisher Scientific, each one of our 65,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.


Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
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