Scheduler, mRNA Operations

Work Schedule

Environmental Conditions

Job Description

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of more than $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD.

The Monza site of Thermo Fisher Scientific is seeking for an Operations Scheduler, for the mRNA Manufacturing Process Unit, dedicated to formulation of mRNA Drug Substances & Drug Products.

The resource will be responsible for developing detailed planning for the manufacturing activities of the technical unit and related services, aiming to achieve the unit's targets.

This role involves coordinating the readiness of the manufacturing department, including the scheduling of:

- new equipment installation and qualification, in collaboration with the MSAT, Equipment and Computer System Validation, Automation and IT departments.

- equipment maintenance and calibration activities, working together with Maintenance and Calibration and Planning.

- production material release process, supporting the Supply Chain and Planning functions.

following the phases of processing, optimizing execution times.

What will you do?

Readiness: 

Ensure the Manufacturing Unit’s readiness concerning the short-term production plan by optimizing the planning of all activities to guarantee plan execution, identifying optimization margins and time reductions, and managing real-time issues to minimize delivery impact. Specifically:

- Monitor and ensure the execution of all activities necessary for production start (e.g., installation, qualification, maintenance and calibration activities of new and existing equipment).

- Monitor and ensure the availability of approved documents (Protocols, MBR, SOP) within necessary timeframes.

- Monitor the availability of approved materials within necessary timeframes in collaboration with Supply Chain & Planning, MSAT and QC Raw Material & Packaging.

Scheduling: 

- Collaborate with the key stakeholders and planning to ensure optimal scheduling of manufacturing department activities, issuing each single detailed batch scheduling, informing all functions involved in the manufacturing activities.

- Analyze the scheduling of all organizational unit activities, identify short and medium-term optimizations, and work with planning to incorporate them into manufacturing plans.

- Understand the scheduling of installation, qualification, maintenance and calibration activities of new and existing equipment, including them into the manufacturing plans and monitoring/tracking their status.

Execution - Schedule Attainment:

- Collaborate with MSAT and Manufacturing departments to ensure scheduled activities are carried out.

- Monitor the execution of production activities through data/KPI collection and analysis and phase monitoring, revising scheduling in case of issues to maintain delivery or interfacing with planning to assess impacts on planning.

- Understand, monitor, and analyze micro-stoppages or events that have an impact.

- Interface with QC for the execution of in-process controls (IPC) within the planned timeframes.

- Inform all relevant stakeholders in case of batch execution delays.

Standard Times:

- Collaborate in defining standard times for the manufacturing activities, in cooperation with involved functions.

- Analyze and optimize standard times through performance monitoring and identifying improvements.

- Account for activities in terms of productive staff work hours in the information system for accurate cost control.

Education/ Experience

- MS in Operations Management, Logistics, Industrial Engineering, or proven experience.

Knowledge, Skills, Abilities

- Experience in main Upstream (Media Preparation and Enzymatic reactions in Bioreactors) and in Downstream steps (TFF, Chromatography, Encapsulation, Clarifications/Filtrations).

- Proven experience in scheduling, project coordination roles.

- Excellent organizational and time management skills.

- Strong communication and interpersonal skills.

- Proficiency in scheduling software and tools (e.g., Microsoft Project, SAP).

- Ability to work independently and as part of a team.

- Detail-oriented with the ability to handle multiple tasks simultaneously.

- Problem-solving skills and a proactive approach to managing changes.

Thermo Fisher Scientific is an Equal Opportunity Employer.

Join us, and be part of our Company