Nos aseguraremos de que las personas con discapacidades reciban adaptaciones razonables para participar en el proceso de solicitud de empleo o entrevista de trabajo, para que puedan ejercer las funciones de trabajo esenciales y recibir otros beneficios y privilegios del empleo. Comuníquese con nosotros para solicitar una adaptación.
Sr. Scientist - Clinical Genomics
Share job link
Work Schedule
Standard (Mon-Fri)Environmental Conditions
Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)Job Description
At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.
Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.
Key responsibilities:
The clinical genomics research scientist is responsible for helping develop genomics biomarker strategy and implement on programs. This includes but is not limited to responsibilities for genomics and gene expression profiling (GEP) biomarker assay technology/ platform selection, evaluation of in-house or vendor choice per assay use requirements, development, optimization, qualification/validation and execution of biomarker analysis for translational medicine and clinical programs. Successful candidates must have a strong technical background in genomics and transcriptomics and its application in clinical programs, additional specific requirements listed below:
- Developing genomics and transcriptomics strategies with biomarker leads, data analysis, and trial operations teams.
- Focusing 100% on lab work, requiring onsite attendance.
- Designing and developing genomics/transcriptomics assays, including broad genomic/GEP profiling, pharmacodynamic, target engagement, predictive, and prognostic assays.
- Developing, optimizing, qualifying/validating, and executing biomarker assays, both in-house and with external vendors.
- Overseeing assay/workflow development and analyzing qualification/validation data.
- Providing subject matter expertise and oversight for outsourced studies.
- Drafting experimental plans, qualification protocols, reports, SOPs, technology transfer documents, and study summaries.
- Participating in internal/external collaborations and clinical study teams.
- Assessing and onboarding relevant technologies through due diligence and pilot projects.
- Working closely with data analysis, sample management, and clinical operation teams.
- Providing mentorship and leadership within the lab team.
- Developing efficient genomics processes and best practices.
Education and Experience:
- Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
- Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years’)
- OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
- OR PhD
In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills and Abilities:
- Prior experience working in a CLIA-licensed lab is a plus.
- Must be capable of working and operating in a laboratory environment for the entirety of the work schedule.
- Significant experience with NGS or GEP applications is required.
- Demonstrated experience in assay development for genomics assets, preferably in a pharma, biotech, diagnostic, or clinical lab setting.
- In-depth, hands-on experience with genomics platforms (NGS, qPCR, variant analysis) for assay development, qualification/validation, troubleshooting, and reviewing run QC data.
- Experience with technologies for ctDNA and GEP analysis is critical.
- Understanding of fit-for-purpose genomics assay validation principles for clinical assays.
- Knowledge of clinical sample analysis regulatory and quality frameworks (e.g., GCP, CLIA, CAP, NYDOH) is a plus.
- Strong organizational and collaborative skills are essential.
Working Environment:
Below is listed the working environment/requirements for this role:
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
Able to work upright and stationary and/or standing for typical working hours.
Able to lift and move objects up to 25 pounds
Able to work in non-traditional work environments.
Able to use and learn standard office equipment and technology with
proficiency.
May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
Benefits
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Recibe notificaciones de trabajos similares
¡Error!
Recomendaciones de perfil
Trabajos similares
-
Sr. Scientist - LBA/ADA
Ubicación Lawrenceville, Nueva Jersey, Estados Unidos Id. del empleo R-01304576
Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years’). OR Masters degree and previous experience that provides the knowledge, s...
-
Associate/Group Leader
Ubicación Collegeville, Pensilvania, Estados Unidos Id. del empleo R-01303601
OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 4+ years’). Previous experience that provides the knowledge, skills, and abi...
-
Associate Scientist- Bioanalytical methods
Ubicación Wilmington, Delaware, Estados Unidos Id. del empleo R-01306170
Discover Impactful Work: Associate Scientist will conduct the cell culture lab works in both cell line development (CLD) and cell culture process development (Upstream) teams to support the developmen...
-
Sr Scientist
Ubicación Richmond, Virginia, Estados Unidos Id. del empleo R-01293446
Bachelor's degree or equivalent and relevant formal academic / vocational qualification and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 5+...
-
Sr Scientist
Ubicación Richmond, Virginia, Estados Unidos Id. del empleo R-01306950
Reviews, interprets, and analyzes data for technical, quality and compliance to protocols, methods, SOPs, client criteria and Good Manufacturing Practices (GMP) or Good Laboratory Practices (GLP). Pre...
-
Associate Scientist, Purification Process Science
Ubicación Wilmington, Delaware, Estados Unidos Id. del empleo R-01303063
Conduct routine protein purification to support formulation team’s material needs and cell culture development. Conduct high-throughput protein purification to support cell line development. Experienc...
-
Associate Scientist- Formulations
Ubicación Wilmington, Delaware, Estados Unidos Id. del empleo R-01307509
The role involves designing and executing the experiments, document experimental details, organize the data, and summarize the findings in a technical summary report. The position emphasizes scientifi...
-
Senior Scientist - LCMS
Ubicación Richmond, Virginia, Estados Unidos Id. del empleo R-01301585
Reviews, interprets, and analyzes data for technical, quality and compliance to protocols, methods, SOPs, client criteria and Good Manufacturing Practices (GMP) or Good Laboratory Practices (GLP). Pre...
-
Scientist- HPLC
Ubicación Collegeville, Pensilvania, Estados Unidos Id. del empleo R-01306461
Performs a variety of routine to complex sample preparation and analysis procedures to quantitatively measure pharmaceutical and biopharmaceutical compounds in a variety of formulations and/or biologi...
Los solicitantes de empleo también vieron
-
Clinical Trial Coordinator, Athens/Thessaloniki
Ubicación Athens, Grecia Id. del empleo R-01269537
Shown ability to attain and maintain a good working knowledge of applicable Country Regulations, ICH Good Clinical Practices, and organization/Client SOPs and WPDs for all non-clinical/clinical aspect...
-
Scrum Master - HRSD ServiceNow
Ubicación Remote, México Id. del empleo R-01305014
Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionWe are seeking an experienced Scrum Master to lead our agile team in the development, implementation, and optimization of HR
-
Contract Specialist - FSP dedicated - France
Ubicación Remote, Francia Id. del empleo R-01304889
Negotiates within approved parameters both investigator grant budget negotiation parameters, contractual terms and conditions in per company contractual considerations, client contractual consideratio...
-
CTM
Id. del empleo R-01211806
Job DescriptionAt Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers
-
Vendor Compliance Specialist
Ubicación Lagunilla, Costa Rica Id. del empleo R-01293495
Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionHow will you make an impact?The Vendor Compliance Specialist plays an important role in ensuring vendors meet the organizati
Nos aseguraremos de que las personas con discapacidades reciban adaptaciones razonables para participar en el proceso de solicitud de empleo o entrevista de trabajo, para que puedan ejercer las funciones de trabajo esenciales y recibir otros beneficios y privilegios del empleo. Comuníquese con nosotros para solicitar una adaptación.